Estradiol and progesterone, together.
- OB/GYN reviewed
- HSA/FSA eligible
- Ongoing support
Estrada™
OB/GYN-prescribed hormone therapy
Two hormones. One daily cream.
Bioidentical estradiol and micronized progesterone, together in a prescription made for you. Start with your symptoms. An OB/GYN helps you make sense of what comes next.
- One daily prescription cream
- Four strengths, selected by your OB/GYN
- Unlimited OB/GYN messaging included
- Prepared by a licensed U.S. pharmacy
$179 per month
See if Estrada is right for you90-day supply, billed monthly.
HSA/FSA eligible · ✓ Cancel anytime
Trusted by 20,000+ women
What is Estrada?
Estrada combines bioidentical estradiol and micronized progesterone in one once-daily vaginal cream. An OB/GYN reviews your symptoms and medical history before deciding whether to prescribe it.
What support comes with treatment?
Your OB/GYN reviews your symptoms and medical history before prescribing. Ongoing messaging gives you a place to ask questions about your prescription and discuss how you are feeling.
How do I use it?
Follow the dose, application and storage instructions on your pharmacy label. Your OB/GYN or pharmacist can explain anything that is unclear before you start.
Prescription information
Estrada is a compounded prescription, not an FDA-approved medicine. Your OB/GYN reviews benefits, risks and alternatives before prescribing.
Prescription only. Treatment is subject to OB/GYN approval.
HRT made simple
Less to juggle. More support.
The cream is one part. Your OB/GYN helps guide your care.
A routine with clear directions.
Selected by your OB/GYN.
Your history informs the decision.
Room for questions as you go.
Meet your daily hormone cream
One daily cream. Care that stays with you.
Estradiol and progesterone, prescribed together with support from an OB/GYN.
$179 per month
90-day supply, billed monthly.
- 15% off your first order
- Prescribed by an OB/GYN
- Message your OB/GYN anytime
- Dose adjustments included
- Compounded to order
- Free shipping
- HSA/FSA eligible
- Pay without insurance
- Cancel anytime
Prescription only. Treatment is subject to OB/GYN approval.
Where it shows up
You know when you don't feel like yourself.
Broken sleep. Sudden heat. A shorter fuse. Bring the full picture to your OB/GYN, including the changes that are hard to put into words.
Sleep & night sweats
Waking in the night, restless sleep or sheets that need changing.
Symptoms can have more than one cause. Your OB/GYN determines what needs further assessment and whether treatment is appropriate.
The Soha community
In their own words.
Individual experiences vary.
“You’d have to pry Estrada from my cold, dead hands. I’m never going back.”
Justine C
“Good sleep had become so rare that I started to think it was a myth. Now restful nights feel possible again.”
Johna Z
“My doctor said my hormone levels were ‘normal,’ but I knew I didn’t feel like myself. Within weeks, I felt calmer, happier, and like I could finally enjoy life again.”
Jasmine B
“I don’t feel like an old engine running on fumes anymore. I feel refreshed, capable, and alive again.”
Jada A
“I feel like myself again. It’s as if someone lifted a layer of shrink wrap from my mind and body.”
Nora N
“My husband told me, ‘I missed you so much,’ and it completely broke my heart. I finally feel present with the people I love again.”
Natasha J
“I’m finally feeling human again. Now I just need to give away the dozens of fans I kept everywhere for hot flashes.”
Chaya N
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A simpler daily routine
One cream. A little space in your day.
Estrada brings both prescribed hormones into one metered-pump cream. Your OB/GYN sets your strength and walks you through how to use it.
Know your dose
Follow the directions that come with your prescription.
Follow your pharmacy label.
See if Estrada is right for youInside the formula
Know what goes into your care.
Two hormone ingredients in one prescription cream. Your OB/GYN reviews whether this formulation suits your needs.
Bioidentical describes a molecular structure that matches a hormone made by your body. Ask your OB/GYN why estradiol is being considered in your plan.
Combined with estradiol in the same cream. Your OB/GYN reviews the formulation, strength and any monitoring needed for you.
The base carries the prescribed ingredients. Ask your pharmacist for the full ingredient list, especially if you have allergies or sensitivities.
1 / 1
Estrada is a compounded prescription, not an FDA-approved medicine. Your OB/GYN reviews benefits, risks and alternatives before prescribing.
See if Estrada is right for youUnderstand your options
Different routes. An individual decision.
Compare application, timing and tolerability. The best fit depends on your history and prescription.
| What to consider |  |  |  |
|---|---|---|---|
| Form | Prescription cream | Two dosage forms | Prescription tablets |
| How it is used | Vaginally, as prescribed | Patch and oral medicine | Taken by mouth |
| Ingredients | Estradiol + progesterone | Depends on regimen | Depends on prescription |
| Routine | Follow your label | Different schedules | Follow your label |
| Questions to ask | Application and dose | Skin and pill tolerability | Interactions and dose |
| Treatment choice | Individual review | Individual review | Individual review |
A different route does not by itself make a treatment safer or more effective. Ask about benefits, risks and alternatives for your circumstances.
See if Estrada is right for you
Specialist care, with context
An OB/GYN before, during and after.
Your symptoms, history and priorities. An OB/GYN weighs them together before making a treatment decision.
Your history matters
Share your medications, medical history and what has changed.
Your questions belong here
Discuss benefits, risks and alternatives before you begin.
Your plan can evolve
Bring new concerns and changes to your OB/GYN throughout care.
Every woman should get a straight answer, a real plan, and someone who follows through.
The Soha approach
Personal reviewClear directionsOngoing support
From the Soha Journal
Good information. Better conversations.
Plain-language guides to help you prepare for your OB/GYN conversation.
Could this be perimenopause?
Still having periods, but something feels different? Understand common perimenopause signs, other possible causes and what to discuss with your OB/GYN.
Read the guide
Local or systemic hormone therapy? The difference matters.
Understand local vaginal estrogen, systemic HRT and why the exact prescription matters when discussing perimenopause and menopause care with your OB/GYN.
Read the guide
Starting HRT? Know what happens after the prescription.
Prepare for HRT follow-up: what to track, questions for your clinician, medication instructions and symptoms that need urgent medical attention.
Read the guide1 / 1
General education, not personal medical advice.
How it works
A clear next step. Then someone beside you.
01
Tell us what's changed
A short online quiz asks about your symptoms, your history and what you’re hoping for.
02
An OB/GYN reviews your story
Your answers get an individual review. Treatment is prescribed only if appropriate.
03
Begin with ongoing support
Approved prescriptions ship to your door. Keep asking questions through OB/GYN messaging.
Care that listens first
You don't have to find the perfect words.
Say what feels different. The nights, the heat, the mood, the questions. Your experience is the place to start.
The questions that come later
Your prescription comes with a conversation.
Your Soha care includes unlimited OB/GYN messaging. Ask about your routine, share how you are feeling and discuss changes along the way.
- Questions about your prescription
- Changes in how you feel
- Next steps, explained clearly
Estrada™
Something's changed. Start there.
Start with the quiz. An OB/GYN reviews your answers before deciding whether Estrada is right for you.
Prescription only. Individual assessment required.
Here for your questions
Good questions.
Thoughtful care.
Explore your care, one question at a time.
About Estrada
Estrada is a compounded prescription cream containing bioidentical estradiol and micronized progesterone. It is used once daily as directed, and an OB/GYN decides whether the formulation is appropriate for you.
It describes a hormone with the same molecular structure as one produced in the body. The term does not mean a medicine is risk-free.
No. Estrada is a compounded prescription made for an individual patient by a licensed pharmacy. The FDA does not review or approve compounded medicines for safety or effectiveness.
Follow the application, dose, storage instructions and beyond-use date on your pharmacy label. If anything is unclear, ask your pharmacist or OB/GYN before starting or changing how you use it.
Your care
You can begin by sharing your concerns. An OB/GYN determines whether further evaluation or a diagnosis is needed before treatment.
Your symptoms, medical history and current medications inform an individual review. Your OB/GYN may need additional questions, records or testing before deciding whether to prescribe.
Yes. Your Soha care includes unlimited messaging with an OB/GYN, so you can ask about your routine and discuss how you are feeling as treatment continues.
Share your complete medical history and all medicines or supplements. Some conditions make hormone therapy unsuitable, so include any history of cancer, blood clots, liver disease or unexplained bleeding.
Getting started
Begin with the online quiz. Your answers help an OB/GYN review your symptoms, medical history and whether Estrada is appropriate for you.
Yes. Estrada is available by prescription only. An OB/GYN reviews your information before deciding whether to prescribe it.
Estrada is available in four strengths. Your OB/GYN selects the strength based on your individual review and discusses any changes with you.
If prescribed, a licensed U.S. pharmacy prepares your treatment and ships it to your door. Follow the directions provided with your prescription.
Still have something on your mind?Unlimited messaging with an OB/GYN.
From the Soha community
More stories. Many ways to feel heard.
The individual experiences shared on this page, collected in one place.
Individual experiences vary.
Justine C
“You’d have to pry Estrada from my cold, dead hands. I’m never going back.”
Johna Z
“Good sleep had become so rare that I started to think it was a myth. Now restful nights feel possible again.”
Jasmine B
“My doctor said my hormone levels were ‘normal,’ but I knew I didn’t feel like myself. Within weeks, I felt calmer, happier, and like I could finally enjoy life again.”
Jada A
“I don’t feel like an old engine running on fumes anymore. I feel refreshed, capable, and alive again.”