Bioidentical Estradiol
The estrogen your body used to produce. Cooler nights. Steadier mood. Less dryness.
Estrada™ | Hormonal
Trusted by 20,000+ women
Ready for hormone therapy. Not ready for three prescriptions.
Most HRT is a patch from one appointment and a progesterone pill from another. Estrada™ is both hormones in one cream, in four strengths, adjusted by one OB/GYN who stays on it. No patch. No pill. No stacking. One application, once a day.
- Compounded in a Licensed U.S. Pharmacy
- Bioidentical Estradiol + Progesterone
- One daily cream
OB/GYN-Prescribed TreatmentOB/GYN-Prescribed Treatment
Bioidentical Estradiol + ProgesteroneBioidentical Estradiol + Micronized Progesterone
Made in U.S.ACompounded in a Licensed U.S. Pharmacy
“With few exceptions, there may be no other medication in the modern era that can improve the health outcomes of women on a population level than hormone replacement therapy.”
FDA Commissioner, November 2025
Estrada™ | Hormonal
Designed for the symptoms that actually change your days.
Estrada™ supports:
- Clearer thinking, steadier moods
- Deeper, more restorative sleep
- Fewer hot flashes and night sweats
- Better sex
- Steadier energy
- Less midlife belly fat
- Vaginal health
- Bone health
Managing the list is exhausting. There's one place to start: the hormones.
Estrada™ helps restore your hormones, prescribed by an OB/GYN, so you feel more like you.
See if Estrada™ is right for you
Prescribed by a board-certified OB/GYN.
The Science
How Estrada™ can support your entire body
Progesterone
Estradiol
Base
Bioidentical Estradiol
The estrogen your body used to produce. Cooler nights. Steadier mood. Less dryness.
Bioidentical Progesterone
The calming hormone your body used to produce. Deeper sleep. A quieter mind. A protected uterine lining.
Adjusted by your OB/GYN
A dose that fits you now, and changes when you do. Set by a real OB/GYN.
The timeline
What Estrada may look like
for you
Everyone's timeline is different. This is what hormone therapy often looks like in the first two months.
Sleep
Week 2 · The first nights
The nights get quieter.
Progesterone tends to work first. For many women the first thing that changes is sleep. Falling asleep faster, waking less, fewer sheets kicked off at 3am. Not more sleep. Uninterrupted sleep. Women describe it as the first real sign.
A guide, not a schedule of results or appointments. Follow your care plan; OB/GYN messaging is available throughout.
The Soha community
Every woman has a story.
Individual experiences vary.
“You’d have to pry Estrada from my cold, dead hands. I’m never going back.”
“Good sleep had become so rare that I started to think it was a myth. Now restful nights feel possible again.”
“My doctor said my hormone levels were ‘normal,’ but I knew I didn’t feel like myself. Within weeks, I felt calmer, happier, and like I could finally enjoy life again.”
“I don’t feel like an old engine running on fumes anymore. I feel refreshed, capable, and alive again.”
“I feel like myself again. It’s as if someone lifted a layer of shrink wrap from my mind and body.”
“My husband told me, ‘I missed you so much,’ and it completely broke my heart. I finally feel present with the people I love again.”
“I’m finally feeling human again. Now I just need to give away the dozens of fans I kept everywhere for hot flashes.”
“Remembering a dream again caught me by surprise. Such a small thing, but it made a better night's rest feel real to me.”
“The hot flashes don't interrupt my whole day the way they used to. My nights feel more comfortable too, and I can bring questions to my OB/GYN as things change.”
“A clearer head is the biggest thing for me. I'd really missed being able to think straight.”
“I still get annoyed. I'm a person! But every tiny inconvenience doesn't need to become the main event anymore.”
“I'm less worn out and can focus more easily. Having a way to message my OB/GYN means I don't have to save up every little question.”
“Having an OB/GYN who listens makes it easier to ask the questions I've been keeping to myself.”
Anxiety out of nowhere??I am snapping over everything.Forgetting words all the timeWhy are we waking up at 3am?38 and I was told I'm too young
Estrada™ is for
The symptoms nobody warned you about.
- Waking at 3am and staying awake
- Losing the word mid-sentence
- Anxiety that came out of nowhere
- Aching joints nobody can explain
- Sex you've stopped wanting, or that hurts when you do
- Snapping at people you love
Pick the ones that sound like you. That's where your OB/GYN starts.
See if Estrada™ is right for youEstrada™ is for
The symptoms nobody warned you about.
- ✓Waking at 3am and staying awake
- ✓Losing the word mid-sentence
- ✓Anxiety that came out of nowhere
- ✓Aching joints nobody can explain
- ✓Sex you've stopped wanting, or that hurts when you do
- ✓Snapping at people you love
Pick the ones that sound like you. That's where your OB/GYN starts.
See if Estrada™ is right for you
How it works
Getting started is simple
Estrada™ Quiz
Estrada · Hormonal
Relief starts here.Prescribed by an OB/GYN.
Which of these have you noticed in the past month? Choose all that apply.
- Fatigue
- Insomnia
- Brain fog
Step 1
Tell us what's going on
A short online intake about your symptoms, history, and goals. About two minutes, no appointment. Not a checklist. An OB/GYN reads every answer.
How we compare
Take the 2-min quizSame hormones. Different routes.
How estrogen enters the body changes what you deal with.
 |  |  | |
|---|---|---|---|
| Liver metabolism | Bypasses liver | Processed by liver | Bypasses liver |
| Progesterone | Included | Separate pill | Separate pill |
| Daily routine | One application | Daily tablet, plus progesterone | Patch changed 1–2× weekly, plus a pill |
| Route effects | No first-pass, no adhesive | First-pass raises clotting proteins | Adhesive can irritate or peel |
| Targeted support | Local + systemic | Systemic only | Systemic only |
| Dose adjustment | Multiple strengths, set by your OB/GYN | Fixed tablet strengths | Limited patch sizes |
| Prescribed by | Board-certified OB/GYN | Varies | Varies |
Estrada™ (Vaginal)
- Liver metabolism
- Bypasses liver
- Progesterone
- Included
- Daily routine
- One application
- Route effects
- No first-pass, no adhesive
- Targeted support
- Local + systemic
- Dose adjustment
- Multiple strengths, set by your OB/GYN
- Prescribed by
- Board-certified OB/GYN
The science behind it
Why Soha's treatment works when others haven't
Every Soha treatment is built on BioAlign™. It's a simple idea: use hormones identical to your own, in the amounts your body actually needs. It's the reason women who've tried everything else finally feel like themselves again. Here's what to expect.
Matched to your body's chemistry. Dosed to restore its natural balance.
Made with hormones identical to the ones your body naturally produces.
Created by women who understand this chapter because they're living it too.
What’s included with your care.
- Prescribed by an OB/GYN
- Message your OB/GYN anytime
- Dose adjustments included
- Compounded to order
- Free shipping
- HSA/FSA eligible
- Pay without insurance
- Cancel anytime
How it works
Getting started is simple
Estrada™ Quiz
Estrada · Hormonal
Relief starts here.Prescribed by an OB/GYN.
Which of these have you noticed in the past month? Choose all that apply.
- Fatigue
- Insomnia
- Brain fog
Step 1
Tell us what's going on
A short online intake about your symptoms, history, and goals. About two minutes, no appointment. Not a checklist. An OB/GYN reads every answer.
An OB/GYN before, during, and after.
Swipe to explore your care
Here for your questions
Good questions.
Thoughtful care.
Explore your care, one question at a time.
Safety
Benefits and risks depend on your history and the treatment. Your OB/GYN should review both, including alternatives, before prescribing.
It describes a hormone with the same molecular structure as one produced in the body. The term does not mean a medicine is risk-free.
If you have a uterus and are considering systemic estrogen, ask your OB/GYN how the uterine lining will be protected and which formulation is appropriate.
Hormone medicines can cause side effects. Ask about those associated with your prescription and report new symptoms to your OB/GYN.
Some health conditions make treatment unsuitable. Share your complete medical history, including cancer, blood clots, liver disease, or unexplained bleeding.
The WHI studied particular hormone regimens and health outcomes. Ask your OB/GYN how the evidence relates to your age, history, and proposed treatment.
Breast-cancer risk can differ by regimen and duration. Discuss your personal and family history with your OB/GYN rather than assuming all hormone treatments have the same risks.
There is no set end date. You and your OB/GYN revisit it as you go.
Heart health belongs in your risk review. Hormone therapy should not be started solely to prevent heart disease.
Clot risk depends on your history and treatment. Using a cream does not establish that your prescription has no clot risk.
Your OB/GYN decides whether tests or other monitoring are needed. Bring previous results if you have them.
List all prescriptions, over-the-counter medicines, and supplements so your OB/GYN can review possible interactions.
Getting a prescription
You can begin by sharing your concerns. An OB/GYN determines whether further evaluation or a diagnosis is needed before treatment.
The introductory quiz is brief. A prescribing review may require additional questions or information.
Yes. Soha is OB/GYN reviewed. Your plan also includes unlimited messaging with an OB/GYN for ongoing questions and support.
Yes. Unlimited messaging with an OB/GYN is included in your Soha plan, so you can ask questions about your routine and discuss how you are feeling as treatment continues.
Using the cream
Once a day. When you start, your OB/GYN goes over the timing with you.
Follow the instructions supplied with your prescription, or ask your pharmacist or OB/GYN what to do.
Use the storage instructions and beyond-use date on your pharmacy label.
Who can start
Care comes from an OB/GYN licensed in your state. Confirm availability for your location before beginning treatment.
No. HSA and FSA funds can be used, though.
This service is for adults. Your OB/GYN also considers your age, symptoms, and health history when assessing whether treatment is appropriate.
Shipping
Timing depends on prescribing review and pharmacy preparation. Check your order updates for the expected dispatch date.
Yes. The outer box is plain and gives no hint of what is inside.
Whenever you like, from your account, and there is no fee for it.
Still have something on your mind?Unlimited messaging with an OB/GYN.
From the Soha Journal